题目：Exploring diverse cellular dynamics by quantitative single-cell imaging:

from basic science to new cancer therapeutic strategies（通过单细胞定量成像探索不同的细胞动力学：从基础科学到新的癌症治疗策略）

报告人：史珏博士（香港浸会大学物理系副教授）


时间：2016年5月7日上午10：30-11：30

地点：beat365中国唯一官方网站（南校区），冼为坚堂117报告厅



报告简介：

My main research interest is to combine quantitative measurements with empirical modeling to explore the mechanism of collective behaviors in cellular processes and diseases. In particular, through image-based single cell analysis and kinetic modeling, I would like to characterize and quantify cellular changes induced by anticancer drugs across different cancer types. This would not only improve our understanding of kinetic and molecular alterations in a complex cellular network, induced by local perturbations from drug treatment, but also provide important insight into principles of control and regulation underlying systematic behavior.

The major experimental approach is microscopy, including high-throughput automatic microscopy, and real-time live cell microscopy based on phase-contrast and fluorescence imaging. Other cellular and molecular biology techniques are also employed, such as RNA interference (RNAi), cloning to generate fluorescent reporter cell lines, immunofluorescence, etc. Development of image analysis tools and computational algorithms for kinetic modeling is another essential component of my research interest, as I believe being quantitative is the key to unravel the complexity of bio-systems.


报告人简介：

史珏博士，香港浸会大学物理系副教授

B.S. in Physics at Zhongshan University, China, PRC

M.A. in Science Education,
Ph.D. in Biophysics at the University of Michigan, Ann Arbor

Postdoctoral in Department of Systems Biology, Harvard Medical School