摘要:My lab at Cornell develops innovative single molecule techniques to stretch, unzip, and twist single DNA molecules, to track motions of proteins that translocate along and rotate around DNA, and to measure forces and torques generated by these motors. We apply these approaches to study the mechanisms of DNA packaging, transcription, and replication. In this lecture, I will focus on our studies of chromatin dynamics and how our initial efforts to map out the chromatin landscape have led us to insights into epigenetic inheritance. In addition, I will also discuss our ongoing efforts to make these precision mechanical measurements high throughput on a nanophotonic platform.
报告人简介:Professor Michelle D. Wang is a well-known scientist in the field of single molecule biophysics. She has received many awards including the Keck Foundation Distinguished Young Scholar in Medical Research Award, the Beckman Young Investigator Award, the Alfred P. Sloan Research Fellow Award, and the Damon Runyon Scholar Award etc.She is now a professor in Physics department in Cornell,an HHMI investigator and Fellow of the American Physical Society.